Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
RGD |
Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns.
|
21171972 |
2010 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Effect of the G-308A polymorphism of the tumor necrosis factor alpha gene on the risk of ischemic heart disease and ischemic stroke: a meta-analysis.
|
17452160 |
2007 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
LHGDN |
The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke.
|
14681891 |
2003 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Following multivariate adjustment, carriers of the TNF-alpha (-308)A allele, the IL-1-RA 2* allele or the IL-6 (-174)C allele appeared to have an increased risk of stroke in association with a febrile episode prior to strokes.
|
16879054 |
2006 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
LHGDN |
The aim of this replication study was to confirm our previous findings of associations between the TNF(-308) G/A, IL4R 503 S/P, and ADRB2 27 Q/E polymorphisms and large vessel stroke risk.
|
17600229 |
2007 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the interleukin-1 receptor antagonist and tumor necrosis factor-alpha genes, but not the interleukin-1beta gene.
|
15036607 |
2004 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
CTD_human |
The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke.
|
10950380 |
2000 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
BEFREE |
The aim of this replication study was to confirm our previous findings of associations between the TNF(-308) G/A, IL4R 503 S/P, and ADRB2 27 Q/E polymorphisms and large vessel stroke risk.
|
17600229 |
2007 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
BEFREE |
TNF-α and PON total methylation levels correlated each other (r = 0.44; p = 0.031), especially in stroke patients (r = 0.72; p = 0.008).
|
24500802 |
2014 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
Tumor necrosis factor, which exists both as a soluble (solTNF) and a transmembrane (tmTNF) protein, plays an important role in post-stroke inflammation.
|
31440125 |
2019 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
<b>Background:</b> Tumor necrosis factor-a-induced protein 8-like 2 (TIPE2) is a novel regulator of immunity and protects against experimental stroke.
|
30588195 |
2018 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
BEFREE |
These findings indicate the important roles that TNF-α and IL-1β serum levels play regarding the risk of PSD, particularly during the acute phase of stroke and in patients with genetic susceptibility.
|
28844626 |
2017 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
These data provide evidence that serum TNF-α and IL-1β concentrations are related to poor long-term outcomes after stroke in the presence of particular alleles.
|
29161722 |
2018 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Up-regulated TNF-α expression has also been found in various neurodegenerative diseases such as cerebral malaria, AIDS dementia, Alzheimer's disease, multiple sclerosis, and stroke, suggesting a potential pathogenic role of TNF-α in these diseases as well.
|
21298033 |
2011 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
In inflammatory cytokines, increased cytokines [including interleukin (IL) 1beta, IL-18, tumor necrosis factor alpha] after stroke lead to depression.
|
19891854 |
2009 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
BEFREE |
It was examined whether G to A promoter polymorphism in the tumor necrosis factor-alpha gene at position -308 affects the risk of stroke.
|
16473522 |
2006 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
Quantitative assessment of stroke outcome was evaluated by measuring infarct volume (by magnetic resonance imaging), cerebral blood flow (by laser speckle imaging), neurological and sensory-motor outcome, and postischemic thrombo-inflammation (platelet thrombi, fibrin, neutrophil, phospho-NFκB [nuclear factor κB], TNFα [tumor necrosis factor α], and IL1β [interleukin 1β]).
|
30909835 |
2019 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
The aim of this study was to evaluate the association of genetic variants within the genes encoding tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-3 (MMP-3), with stroke.
|
21219546 |
2011 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
There is increasing evidence on the role of proinflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in the occurrence and outcome of stroke.
|
15733973 |
2005 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
Stroke survivors (50-76 years) underwent a fasting blood draw for measurement of TNF-α, IL-6, CRP, serum amyloid A, sICAM-1, sVCAM-1, and bilateral vastus lateralis biopsies before and after RT.
|
27955950 |
2017 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Serum levels of TNF-α, C-reactive protein (CRP), IL-4, IL-6, IL-10, IL-17, IL-23, and TGF-β increased, whereas serum level of IFN-γ decreased at all time points after stroke.
|
27682880 |
2017 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
This study suggests that delirium is not scarce in patients with AIS admitted to the non-intensive stroke unit, and that delirium developing after AIS seems not to be associated with serum TNF-alpha, IL-1 beta, IL-18, BDNF and NSE but is associated with length of hospital stay and stroke severity.
|
27816188 |
2017 |
Cerebrovascular accident
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Following multivariate adjustment, carriers of the TNF-alpha (-308)A allele, the IL-1-RA 2* allele or the IL-6 (-174)C allele appeared to have an increased risk of stroke in association with a febrile episode prior to strokes.
|
16879054 |
2006 |
Cerebrovascular accident
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Quantitative PCR analysis of whole cell lysate as well as flow-sorted myeloid cells from the perilesional cortex showed increased cellular interleukin 1 beta (IL-1β), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α) mRNA levels but reduced plasma levels of these cytokines in MS P2X4R KO mice after stroke.
|
28751018 |
2017 |
Cerebrovascular accident
|
0.600 |
Biomarker
|
group |
BEFREE |
We investigated the role of inflammatory genes IL1B, IL6, MPO, and TNF in stroke susceptibility and recovery in a population sample of 672 patients and 530 controls, adjusting for demographic, clinical and lifestyle risk factors, and stroke severity parameters.
|
21407237 |
2011 |